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Text lagu It's a Small World disimpan dalam sel bakteri

Dimulai oleh reborn, Februari 21, 2007, 05:11:12 PM

« sebelumnya - berikutnya »

0 Anggota dan 1 Pengunjung sedang melihat topik ini.

reborn

Setelah jaman batu, nulis di kertas, dunia digital pake CD atau harddisk, sekarang data bisa disimpan di DNA... kewl  8) Padahal tahun 2003 ini artikelnya, sekarang dah sampe mana yahh  ???

trnmag.com/Stories/2003/012903/Data_stored_in_live_cells_012903.html

KutipThe researchers used artificial DNA sequences to encode portions of the text of the children's song It's a Small World, added the sequences to bacteria DNA, allowed the bacteria to multiply, then extracted the message part of a DNA strand and retrieved the encoded information.

Because DNA is passed down through generations of living organisms, information stored this way should survive for as long as the line of organisms survives, said Pak Wong, a chief scientist at the Pacific Northwest National Laboratory. DNA is made up of four bases attached to a sugar-phosphate backbone. Different sequences of the four bases can represent digital information.

peregrin

menarik  ;) ... tp utk problem mutasi itu gimana cara mengatasinya ya? btw, ternyata kecoak bisa jd berguna jg suatu saat y, barangkali  ;)

ini ada artikel lain, nyebut2 Feynman pula yg kayanya tokoh fave ya di forum ini?  ;)

[pranala luar disembunyikan, sila masuk atau daftar.]

Message In A DNA Bottle
Matthew Herper, 10.24.05, 9:00 AM ET

Put your data on a hard drive, and it may be safe for a decade--assuming the drive doesn't break. But what if you want to keep information safe for hundreds of millions of years?

You might try DNA.

The power of DNA as a storage device was first recognized only six years after the molecule was discovered. In a prescient 1959 lecture at the California Institute of Technology, Richard Feynman, one of the most admired physicists of the 20th century, forecast that miniaturized technology would likely change the world--essentially predicting the digital revolution. Then he pointed out that nature had already done the microchip one better in the form of deoxyribonucleic acid.

In a small bundle of atoms at the center of every cell, Feynman noted, all the information needed to create a human, an amoeba or a tomato was encoded. As in so much else, Feynman was ahead of his time. Scientists have calculated that DNA may be the ideal storage medium. A mere pound of DNA could hold all the data that has ever been saved on any computer.

But harnessing that computational power has turned out to be tough. The first working computer made entirely of DNA was created in 1994 by Leonard Adleman, a computer scientist at the University of Southern California. In a teaspoon of water, he used a series of biochemical reactions to solve the famous "traveling salesman" problem (basically, how many ways can you get from New York to Cleveland while stopping in seven other cities in between?). The promise of the approach was that because each piece of DNA can function essentially as its own computer, it might be possible to use it to do as many as a quadrillion computations at once.

Unfortunately, pulling that trick off turns out to be easier said than done. Adleman himself has managed to solve a 20-variable problem with a DNA computer. But many researchers who flooded into the field of DNA computing after Adleman's initial paper have now moved on to building tiny machines out of DNA molecules instead. The problem: Accessing all the information in a molecule of DNA turns out to be very cumbersome.

"My own personal conclusion is that the DNA computing paradigm isn't going to provide a powerful computing platform for solving problems," says Lloyd Smith, a scientist at the University of Wisconsin-Madison who has done DNA computing work, but intends not to renew his grant applications related to the topic. "It's cute, but I don't know that it's an important concept."

Some researchers who have stuck with the idea of storing information in DNA are actually moving away from the idea that the molecule can save massive amounts of information. Instead, they are focusing on saving smaller messages for long periods of time--perhaps outlasting all of the books, hard drives and backup tapes that civilization has produced.

DNA in organisms is constantly evolving, but error-correcting machinery keeps messages from degrading over time. Pak Chung Wong, a researcher at Pacific Northwest National Laboratory, points out that some strains of bacteria have kept their DNA pretty much intact for millions of years. He and his colleagues have developed a technique for implanting as many as 100 words into an organism's genome and marking it off so that the message is protected against errors.

Wong and his colleagues showed that they could implant a message (they used lyrics from "It's A Small World After All") into the genome of bacteria. A whole family of bacteria with the message can be created, and even after hundreds of generations, the message was still intact. Wong notes that it would be possible to send a message to the future in a particularly hardy organism--such as a bacteria or a cockroach, that would survive a nuclear war. More practically, companies that create genetically modified organisms could use the technology to create a kind of DNA watermark to keep their intellectual property from being stolen.

Beyond providing a way for Genentech (nyse: DNA - news - people ) or Monsanto (nyse: MON - news - people ) to keep other companies from stealing their genetically engineered organisms, such a technology could be the best way we have of sending a message to the distant future. Forget the engravings on the Voyager satellites. This message could last as long as there is any life on earth. The only question: what would we say?


  
Free software [knowledge] is a matter of liberty, not price. To understand the concept, you should think of 'free' as in 'free speech', not as in 'free beer'. (fsf)

reborn

Kutip dari: peregrin pada Februari 21, 2007, 07:09:59 PM
menarik  ;) ... tp utk problem mutasi itu gimana cara mengatasinya ya? btw, ternyata kecoak bisa jd berguna jg suatu saat y, barangkali  ;)

hmm.... pas sama bidangnya peregrin ternyata ini yah, pemetaan genetik? Update terbarunya gmn nih  ;D

Kutipini ada artikel lain, nyebut2 Feynman pula yg kayanya tokoh fave ya di forum ini?  ;)

Masa sih? Siapa tuh fansnya  ::)

Wah ini artikel lanjutannya ternyata, 2005 n ada risetnya si Wong ini juga. Ternyata udah ada komputer pake DNA ini yah? wew... pengen tau  :o

Kutip
Some researchers who have stuck with the idea of storing information in DNA are actually moving away from the idea that the molecule can save massive amounts of information. Instead, they are focusing on saving smaller messages for long periods of time--perhaps outlasting all of the books, hard drives and backup tapes that civilization has produced.

Kalo emang gak bisa nyimpen data yang cukup besar, mungkin ada penerapan lain yang bisa dipake dari sini. Kira2 apa yahh  ??? Pengganti iPod  ;D


peregrin

Kutiphmm.... pas sama bidangnya peregrin ternyata ini yah, pemetaan genetik?

yee.. nggak kok  ;D


KutipKalo emang gak bisa nyimpen data yang cukup besar, mungkin ada penerapan lain yang bisa dipake dari sini. Kira2 apa yahh   ??? Pengganti iPod   ;D

hehehe ...  iPod DNA ;D

kayanya masalahnya di retrieve balik info yg disimpan itu yg susah, lama khan kalo mesti ekstraksi DNA-nya dulu trus di-encode balik ke info mula2. Tp kalo utk archive information aja ya bisa sih mestinya. Kalo utk DNA computing gak tahu deh  ;D

KutipThe researchers used artificial DNA sequences to encode portions of the text of the children's song It's a Small World, added the sequences to bacteria DNA, allowed the bacteria to multiply, then extracted the message part of a DNA strand and retrieved the encoded information.




Free software [knowledge] is a matter of liberty, not price. To understand the concept, you should think of 'free' as in 'free speech', not as in 'free beer'. (fsf)

reborn

Kutipyee.. nggak kok  ;D

kalo gak salah kemaren bilangnya gitu. ngembangin tools buat para biologists untuk bisa interpretasi info2 dalam DNA.

Kutip
hehehe ...  iPod DNA ;D

kayanya masalahnya di retrieve balik info yg disimpan itu yg susah, lama khan kalo mesti ekstraksi DNA-nya dulu trus di-encode balik ke info mula2. Tp kalo utk archive information aja ya bisa sih mestinya. Kalo utk DNA computing gak tahu deh  ;D

Masih buta, itu aja baru liat artikelnya barusan. Hunting lagi lanjutannya  :-\

peregrin

Kutipkalo gak salah kemaren bilangnya gitu. ngembangin tools buat para biologists untuk bisa interpretasi info2 dalam DNA.

nggak kok  ;D


KutipWong and his colleagues showed that they could implant a message (they used lyrics from “It’s A Small World After All”) into the genome of bacteria. A whole family of bacteria with the message can be created, and even after hundreds of generations, the message was still intact. Wong notes that it would be possible to send a message to the future in a particularly hardy organism--such as a bacteria or a cockroach, that would survive a nuclear war.

yg aq nggak ngerti, khan mesti ada agreement tuh gimana translate information yg kita simpan ke DNA code-nya. Jangan2 setelah ratusan tahun, information yg disimpan di DNA tu gak bisa di-retrieve gara2 gak tahu gmn cara breaking code-nya hehehe ... perlu cryptologist dong di masa depan utk breaking DNA code  ;D

aah bisa jadi novel baru nih ... "Indiana Jones and the Lost of DNA Sceptre"  ;D kekkekee......


btw, aq kan gaptek, gak ngerti soal computer, so kalo yg lain mo baca2 (dan ceritain versi for kids-nya ntar  :D), ini deh bbrp pdf, monggo  ;D

btw, bisa buka ini nggak? ada step-by-step experiment-nya Adleman yg pertama kali punya ide pake DNA utk mecahin problem travelling salesman itu. Aq coba akses jurnal science-nya gak bisa kali ini  >:(
arstechnica.com/reviews/2q00/dna/dna-1.html


Singkatnya (yg gak jelas  ;)):
KutipIn 1994, Leonard Adleman introduced the idea of using DNA to solve complex mathematical problems. Adleman, a computer scientist at the University of Southern California, came to the conclusion that DNA had computational potential after reading the book "Molecular Biology of the Gene," written by James Watson, who co-discovered the structure of DNA in 1953. In fact, DNA is very similar to a computer hard drive in how it stores permanent information about your genes.
Adleman is often called the inventor of DNA computers. His article in a 1994 issue of the journal Science outlined how to use DNA to solve a well-known mathematical problem, called the directed Hamilton Path problem, also known as the "traveling salesman" problem. The goal of the problem is to find the shortest route between a number of cities, going through each city only once. As you add more cities to the problem, the problem becomes more difficult. Adleman chose to find the shortest route between seven cities.

You could probably draw this problem out on paper and come to a solution faster than Adleman did using his DNA test-tube computer. Here are the steps taken in the Adleman DNA computer experiment:

Strands of DNA represent the seven cities. In genes, genetic coding is represented by the letters A, T, C and G. Some sequence of these four letters represented each city and possible flight path.
These molecules are then mixed in a test tube, with some of these DNA strands sticking together. A chain of these strands represents a possible answer.
Within a few seconds, all of the possible combinations of DNA strands, which represent answers, are created in the test tube.
Adleman eliminates the wrong molecules through chemical reactions, which leaves behind only the flight paths that connect all seven cities.

computer.howstuffworks.com/dna-computer.htm

Free software [knowledge] is a matter of liberty, not price. To understand the concept, you should think of 'free' as in 'free speech', not as in 'free beer'. (fsf)

reborn

wew... si tante tukang koleksi pdf nih  :o segala topik ada  :o

Kutipaah bisa jadi novel baru nih ... "Indiana Jones and the Lost of DNA Sceptre"  ;D kekkekee......

Haha... imajinasinya ;D langsung dimulai aja bikin dari skrg, 100 tahun lagi booming deh  ;D

Kutipbtw, aq kan gaptek, gak ngerti soal computer, so kalo yg lain mo baca2 (dan ceritain versi for kids-nya ntar  :D), ini deh bbrp pdf, monggo  ;D

Dah disedot, thanks yahh  :D for kids ? ngeledek balik ini  ;)

Kutipbtw, bisa buka ini nggak? ada step-by-step experiment-nya Adleman yg pertama kali punya ide pake DNA utk mecahin problem travelling salesman itu. Aq coba akses jurnal science-nya gak bisa kali ini  >:(

IE kenapa gak bisa yah buka yang begitu  ???

peregrin

Kutipwew... si tante tukang koleksi pdf nih  :o  segala topik ada   :o

lha kalo ini mah tinggal search aja pakde, khan ada google  ;)


KutipIE kenapa gak bisa yah buka yang begitu  ???   btw dah dicoba, ada 5 pages :

bisa kok  :D ... cm gak tahu gratis gak buat reborn dll gitu, soalnya pdf-nya gak bisa di-download ... tp thanks yah udah kasih link-nya satu2 ... reborn aja d yg baca, aq angkat tangan  ;D ... gaptek dan bkn org fisika/math nih  ;D
Free software [knowledge] is a matter of liberty, not price. To understand the concept, you should think of 'free' as in 'free speech', not as in 'free beer'. (fsf)

reborn

Kutiplha kalo ini mah tinggal search aja pakde, khan ada google  ;)

bedanya peregrin bisa akses yg paid subscriptions  :-[


Kutipbisa kok  :D ... cm gak tahu gratis gak buat reborn dll gitu, soalnya pdf-nya gak bisa di-download ... tp thanks yah udah kasih link-nya satu2 ... reborn aja d yg baca, aq angkat tangan  ;D ... gaptek dan bkn org fisika/math nih  ;D

kirain :P enak aja, lagi nunggu for kids version nih  ::)

peregrin

Kutipbedanya peregrin bisa akses yg paid subscriptions   :-[

cup... cup... jangan nangis ... tenaaang, khan ada kurir tukang bajak di sini ... kalo reborn sih tukang tadah  ;D
Free software [knowledge] is a matter of liberty, not price. To understand the concept, you should think of 'free' as in 'free speech', not as in 'free beer'. (fsf)