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Penulis Topik: Genetic Epidemiology  (Dibaca 2663 kali)

0 Anggota dan 1 Pengunjung sedang melihat topik ini.

Offline peregrin

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Genetic Epidemiology
« pada: Juli 07, 2007, 02:20:43 AM »
Ada seri artikel lengkap tentang genetic epidemiology di The Lancet September-October 2005 termasuk bahasan tentang linkage dan association studies (lihat seri 2-6).

Btw, The Lancet gratis ga yah? Kalau ga bisa akses, silahkan liat artikelnya di arsip nalaryogya bagian medis dan farmasi.

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Genetic Epidemiology 1: Key Concept in Genetic Epidemiology
P. Burton, M. Tobin, J. Hopper

This article is the first in a series of seven that will provide an overview of central concepts and topical issues in modern genetic epidemiology. In this article, we provide an overall framework for investigating the role of familial factors, especially genetic determinants, in the causation of complex diseases such as diabetes. The discrete steps of the framework to be outlined integrate the biological science underlying modern genetics and the population science underpinning mainstream epidemiology. In keeping with the broad readership of The Lancet and the diverse background of today's genetic epidemiologists, we provide introductory sections to equip readers with basic concepts and vocabulary. We anticipate that, depending on their professional background and specialist knowledge, some readers will wish to skip some of this article

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Genetic Epidemiology 7: Genetic epidemiology and public health: hope, hype, and future prospects
George Davey Smith, Shah Ebrahim, Sarah Lewis, Anna L Hansell, Lyle J Palmer, Paul R Burton

Genetic epidemiology is a rapidly expanding research field, but the implications of findings from such studies for individual or population health are unclear. The use of molecular genetic screening currently has some legitimacy in certain monogenic conditions, but no established value with respect to common complex diseases. Personalised medical care based on molecular genetic testing is also as yet undeveloped for common diseases. Genetic epidemiology can contribute to establishing the causal nature of environmentally modifiable risk factors, throught the application of mendelian randomisation approaches and thus contribute to appropriate preventive strategies. Technological and other advances will allow the potential of genetic epidemiology to be revealed over the next few years, and the establishment of large population-based resources for such studies (biobanks) should contribute to this endeavour.
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Offline Hendy wijaya, MD

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Re: Genetic Epidemiology
« Jawab #1 pada: Oktober 15, 2009, 03:43:30 PM »
Bahasan mengenai lingkage analysis sangat bagus dalam buku Introduction to genetic principles yang ditulis david hyde. Atau bisa juga dengan buku medical genetics, dan genetics in medicine.
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