Sejauh yang aku tahu hasil penelitian belum menunjukkan hasil yang konklusif bahwa MSG itu merugikan kesehatan, mengingat ia hanya asam amino glutamat yang mengandung satu molekul natrium..

Mekanisme kerjanya secara pasti sampai saat ini belum diketahui namun diduga memperlama ikatan antara suatu molekul dengan reseptor pengecap pada taste bud. Oleh sebab itu ia sering disebut sebagai taste enhancer atau penguat rasa, sebab ia hanya menguatkan rasa yang sudah ada, bukan menyedapkannya. Sebutan penyedap rasa sebenarnya salah kaprah. Kalau dari awal memang masakannya ga enak ya malah tambah ga enak kalau ditaburi MSG.

Itu yang belum bisa dijelaskan bung..apakah ada hasil penelitiannya yang menyebutkan demikian atau hanya laporan kasus?

kalo di daftar bahan tambahan obat di eropa msg masi ada dalam list yang masi diperbolehkan dipake.

Dari kuliah professor farmakologi kita.. Itu katanya.. Toksisitas MSG bikin tetraplegia.

Ingat..kata2 ahli termasuk urutan terakhir sebagai sumber acuan. Minta hasil penelitian atau journal yang menyebutkan demikian. "Katanya" tidak bisa dipakai sbg referensi yg reliable. Ada journal penelitian yang menyebutkan efek jangka panjang penggunaan MSG?Atau ada hasil meta analysisnya?Sebelum hasil penelitian konklusif, setiap pernyataan bisa bermakna spekulatif dan seharusnya tidak disebarkan sebagai fakta, sebab akan memicu keresahan.

Bung momod ada journal ttg MSG?menarik nih..

Terus...terus?Jadi belum ada hasil penelitiannya?

Tapi kalau uni eropa saja belum melarang penggunaan MSG di masyarakatnya berarti hasil penelitiannya masih belum konklusif kan?

MSG masi dipake sebagai bahan tambahan dalam produk farmasi dan makanan di eropa dan amerika. buktinya dalam handbook of pharmaceutical excipients terbaru bahan ini masih ada. ini bahasan mengenai safety-nya:

Monosodium glutamate is widely used in foods and oral pharmaceutical formulations. It is generally regarded as moderately toxic on ingestion or intravenous administration. Adverse effects include somnolence, hallucinations and distorted perceptions, headache, dyspnea, nausea or vomiting, and dermatitis. The lowest lethal oral dose in humans is reported to be 43 mg/kg.(1) The use of
monosodium glutamate in foods has been controversial due to the so-called ‘Chinese Restaurant Syndrome’ (see Section 18), although it is generally regarded as safe at intake levels of up to 6 mg/kg bodyweight.(2) In Europe, total glutamate intake from food ranges from 5–12 g/day.(2)
There has been a report of a foreign body granuloma caused by monosodium glutamate after a BCG vaccination.(3)

Regulatory Status
GRAS listed. Accepted in Europe for use as a food additive in certain applications. Included in the FDA Inactive Ingredients Database (oral syrup). Included in nonparenteral medicines licensed in the UK. Included in subcutaneous vaccine injections.

Comments
Monosodium glutamate has been associated with reports of adverse reactions termed ‘Chinese Restaurant Syndrome’ after it was first self-reported by a physician who regularly experienced numbness and palpitations after consuming Chinese food.(4) Subsequent to this first report, numerous other anecdotal reports
of adverse reactions to monosodium glutamate were made, with symptoms occurring at doses of 1.5–12 g. Reactions include paresthesias or a skin burning sensation, facial pressure or tightness sensation, and substernal chest pressure. Severity of reaction corresponded with increased dose. Reports of ‘Chinese Restaurant Syndrome’ in children are rare. A variety of other adverse reactions
to monosodium glutamate have also been reported including flushing, asthma, headache, behavioral abnormalities, and ventricular tachycardia.(5–7)
Placebo-controlled, blinded, trials of monosodium glutamate consumption have, however, largely failed to reproduce the full effects of ‘Chinese Restaurant Syndrome’ as it was originally described, and symptoms may be simply due to dyspepsia.( Some dose-dependent adverse reactions may be attributed to monosodium glutamate, with doses of 5 g producing reactions in 30% of
individuals tested.(9) In the USA, the FDA has stated that monosodium glutamate and related substances are safe food ingredients for most people when used at ‘customary’ levels.(10–12)
Monosodium glutamate monohydrate 32 g is approximately equivalent to anhydrous monosodium glutamate 29 g or glutamic acid 25 g. Each gram of monosodium glutamate monohydrate represents 5.3 mmol (5.3 mEq) of sodium.
A specification for monosodium glutamate is contained in the Food Chemicals Codex (FCC).(13)
The EINECS number for monosodium glutamate is 205-538-1.
The PubChem Compound ID (CID) for monosodium glutamate is 23689119.