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Drug-induced Osteoporosis

Dimulai oleh syx, Desember 09, 2010, 07:32:17 AM

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syx

The elderly population is at risk for polypharmacy and, therefore, also at risk for drug-induced osteoporosis (DIOP). Epidemiologic studies provide valuable information about medications that may place patients at risk for DIOP. While glucocorticoids are the most common cause of DIOP, the use of several other therapeutic agents can place patients at risk for significant bone loss and fracture. These medications include, but are not limited to, aromatase inhibitors, gonadotropin-releasing hormone agonists, thyroid replacement therapy, antiepileptics, antidepressants, antipsychotics, lithium, gastric acid lowering agents, thiazolidinediones, loop diuretics, heparins and warfarin, vitamin A and cyclosporine.

Astrawinata G

kenapa ya kortikosteroid menyebabkan osteoporosis? lupa saya ???
Best Regards,


Astrawinata G

Huriah M Putra

Lalala~
KutipIt lowers bone formation thus favoring development of osteoporosis in the long term. Cortisol moves potassium out of cells in exchange for an equal number of sodium ions as mentioned above.[36] This can cause a major problem with the hyperkalemia of metabolic shock from surgery. Cortisol reduces calcium absorption in the intestine.
.:::::::. [pranala luar disembunyikan, sila masuk atau daftar.] .:::::::.
[move]OOT OOT OOT..!!![/move]

Astrawinata G

okeh :) thanks Prof Hur.....tapi kayak deja vu gitu, kayaknya kortiko menyebabkan disfungsi osteoblas atau peningkatan aktivitas osteoklas...lupa yang mana, atau malah lupa itu ada apa kagak
Best Regards,


Astrawinata G