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Unsolved problems in chemistry

Unsolved problems in chemistry tend to be questions of the kind "Can we make the X chemical compound?" and are solved rather quickly, but here are some persistent questions with deep implications:

    * Solvolysis of the norbornyl cation: Why is the norbornyl cation so stable? Is it symmetrical? This problem has been largely settled for the unsubstituted norbornyl cation, but not for the substituted cation.
    * On-water reactions: Why are some organic reactions accelerated at the water-organic interface?
    * Better-than perfect enzymes: Why do some enzymes exhibit faster-than-diffusion kinetics? See: Enzyme kinetics.
    * Feynmanium: What are the chemical consequences of having an element (137) whose electrons must travel faster than the speed of light? Problem actually occurs at Element 139 (eka-actinium/dvi-lanthanum), since “A complete analysis involving relativity reduces the speed of electrons, therefore allowing stable 1s orbits in the element 138 (Uto).”
    * Protein folding problem: Is it possible to predict the secondary, tertiary and quaternary structure of a polypeptide sequence based solely on the sequence, and environmental information? Inverse protein-folding problem: Is it possible to design a polypeptide sequence which will adopt a given structure under certain environmental conditions?
    * What is the origin of homochirality in amino acids and sugars?
    * Do sterics (electronic repulsion) or electronics (electronic polarization) have a greater effect on chiral induction in stereospecific and stereoselective chemical reactions?
    * How can electromagnetic energy (photons) be efficiently converted to chemical energy? (E.g. splitting of water to H2 and O using solar energy.)
    * What are the chemical origins of life? How did non-living chemical compounds generate self-replicating, complex life forms?
    * How does the flow of elements, energy, and electrons (oxidation states) drive the structure of local and global ecosystems?
    * What is the origin of the bond rotation barrier in ethane, steric hindrance or hyperconjugation?

iya rencanaya mau di bahas 1 1 , tapi kemarin kan gw lagi
tau kan , ada yang lagi ultah bro
besok mungkin baru saya post

@alinc

gimana acara ultahnya om? Mantap kahh?? Gak lupa sampein salam gw kan ke yg ultah, salam doang gak pake kado hehe...

Bagaimana membedakan problem2 ini dengan problem2 dalam fisika nuklir/zat padat? Kayaknya kok mirip2 pertanyaan fisika ya